Abstrakt

A Brief Note on Toxicogenomics

Hans Uwe Dahms

Toxicogenomics is a branch of pharmacology focused on the collection, analysis, and preservation of statistics on gene and protein activity inside a specific cell or tissue of an organism in response to harmful chemicals. Toxicogenomics is a topic of cell genetics that combines toxicity with genomics or other high-throughput molecular profiling techniques including transcriptomics, proteomics, and metabolomics. Toxicogenomics strives to find molecular expression patterns (i.e., molecular biomarkers) that can be used to predict toxicity or genetic predisposition to it, as well as to unravel the molecular pathways that have transpired in the manifestation of toxicity.