Abstrakt

Pharmaceutical Applications of Insilico methods: A Review.

AR Mullaicharam, and Nirmala Amaresh

Conventionally, drugs were discovered by synthesizing compounds in a time-consuming multi-step processes against a battery of in vivo biological screens and further investigating the promising candidates for their pharmacokinetic properties, metabolism and potential toxicity. Sophisticated insilico approaches has given a tremendous opportunity to pharmaceutical companies to identify new potential drug targets which in turn affect the accomplishment and time of performing clinical trials for discovering new drug targets. The main goal of this review is to summarize the insilico methods in the areas of drug discovery process with emphasis on identifying drug targets, pharmacology and pharmacokinetics.