Abstrakt

To Evaluate the Incidence of Side Effects of Camylofindihydrochloride with Combination of Valethemate Bromide (Epidosin) and Hyoscine � N - Butyl Bromide (Buscopan), on Mother and to Look for Neonatal Outcome.

Sarbhjit Kaur, Paramjit Kaur, Surjit Kaur Bajwa, Surinder Kumari, and Manjit Kaur Mohi

Various drugs have been tried to hasten cervical dilatation so that problems and hazards of prolonged labor both for the mother and fetus are minimized without increasing maternal or perinatal mortality and morbidity. To evaluate the incidence of side effects of camylofindihydrochloride with combination of valethemate bromide (epidosin) &hyoscine N butyl bromide (buscopan), on mother and to look for neonatal outcome. Two hundred cases primigravidae or multigravidae with gestational age of 37 to 40 weeks with single foetus,vertex presentation and no major antenatal complication, admitted to labor room ofgynaecology department of our institutionand divided into 2 groups Group A-100 Cases – labor accelerated by camylofin dihydrochloride and Group B- 100 Cases - labor accelerated by valethemate bromide (epidosin) and hyoscine N butyl bromide. Various side effects and progress of labor and duration of various stages of laborwas noted. Neonate was examined at birth and at 5 minutes for Apgar score. Vomiting occurred in 9% of Anafortan group and 10% Epidosin + Buscopan group. Dryness of Mouth occurred in 7% cases of Anafortan group and 10% cases of Epidosin +Buscopangroup,followed by tachycardia which occurred in 2% cases of Anafortan group and 3% cases of Epidosin + Buscopan group. Apgar score at 1 minute in both the groups was similar i.e 7.97± 0.22 in Anafortan group and 7.97± 0.20 in Epidosin + Buscopangroup.The Apgar score at 5 minutes in both the groups wasquite similar i.e. 8.99 ± 0.1 in Anafortan group and 8.97 ± 0.14 in Epidosin +Buscopan group, so the difference between the two groups is insignificant statistically.