Xiaoyan Xie1,Meilian Peng2,Yan Wang3, Liangzhi Cai1, Yuequan Shi4, Shuxia Xu5, Jiansong Lin5, Mu Xu1*, Qibin Wu1
Background: Fallopian choriocarcinoma is extremely rare and is still treated with a combination of chemotherapy and surgery. We report a case of gestational fallopian tubal choriocarcinoma treated solely with surgery and describe its clinical characteristics, treatment, and follow-up prognosis.
Case presentation: We report a patient who developed fallopian tube choriocarcinoma during the perimenopausal period. After surgical treatment, the patient was diagnosed with histopathology using immunohistochemistry staining combined with short tandem repeat detection, and the diagnosis was confirmed as "gestational fallopian tubal choriocarcinoma". Following the surgery, serum Beta-Human Chorionic Gonadotropin (β-HCG) levels were closely monitored. The patient's β-HCG values demonstrated an exponential decrease, returning to the normal range within six weeks. This trend was maintained for a period of three years. Consequently, the patient did not undergo chemotherapy.
Conclusion: This report offers insights into a simplified surgical approach for treating gestational fallopian tubal choriocarcinoma, designed to meet specific criteria that aim to minimize unnecessary side effects of chemotherapy for these patients.
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