Abstrakt

Recent Sensitivity Pattern of Escherichia Coli in Urinary Tract Infection

R Nalini, J Ezhil Ramya, B Meenakshi, N Palniappan and S Poongodi

The objective of the study is to assess the recent sensitivity pattern of Escherichia coli in Urinary tract infection (UTI).Widespread use of antibiotics has led to the emergence of resistant microorganisms. As the antibiotic sensitivity patterns of the microorganisms are frequently changing, this retrospective analysis was designed to assess the recent antibiotic sensitivity pattern of Escherichia coli (E.coli) in urinary tract infection among the human population. Details of 412 urine culture positive reports for E.coli and their antibiotic sensitivity pattern pertaining to the study period of 12months from June 2012 to May 2013 were collected from Central Microbiology Laboratory of Tirunelveli Medical College and the results were statistically analysed. The antibiotics tested for sensitivity were Amikacin, Gentamycin, Ciprofloxacin, Cotrimoxazole, Nitrofurantoin, Ceftazidime, Ceftriaxone and Cefotaxime. The sensitivity pattern of E.coli to antibiotics in UTI were Nitrofurantoin (85.19%), Amikacin (66.50%), Co-trimoxazole(31.31%), Gentamycin (26.90%), Ceftazidime (26.69%) ,Ciprofloxacin (22.57%), Cefotaxime (22.30%), Ceftriaxone (17.47%). The study highlighted the re-emergence of E. coli sensitive to Nitrofurantoin and marked resistance of E.coli to Aminoglycoside and third generation Cephalosporins.